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Panovir (sofosbuvir-velpatasvir)

Generic Nmae: Sofosbuvir+ Velpatasvir

Manufacturer: Incepta Pharma

Pack Size: 28’s Pot

Originator: Epclusa by Gilead Sciences

Contact For Order:

WhatsApp & WeChat: +8801886229488

Email: aiopharma@outlook.com

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Panovir (sofosbuvir-velpatasvir) is used to treat HCV infection caused by all genotypes. Panovir is widely popular for treating HCV infection.

 

Description: It is a fixed-dose combination tablet containing sofosbuvir and velpatasvir for oral administration. Sofosbuvir is a nucleotide analog HCV NS5B polymerase inhibitor and velpatasvir is an NS5A inhibitor.

 

Indications

Panovir (sofosbuvir-velpatasvir) combination is indicated for the treatment of adult patients with chronic hepatitis C virus (HCV) genotype 1, 2, 3, 4, 5, or 6 infections

– without cirrhosis or with compensated cirrhosis

– with decompensated cirrhosis for use in combination with ribavirin

 

Dosage & Administration

The recommended dosage is one tablet (400 mg of Sofosbuvir and 100 mg of Velpatasvir) taken orally once daily. Recommended treatment regimen:
– Patients without cirrhosis and patients with compensated cirrhosis (Child-Pugh A) – one tablet once daily for 12 weeks
– Patients with decompensated cirrhosis (Child-Pugh B or C) – one tablet once daily and Ribavirin for 12 weeks. The recommended dosage of Ribavirin is based on body weight (1000 mg/day for patients < 75 kg and 1200 mg/day for ≥ 75 kg, in two divided doses/day)

No dosage recommendation can be given for patients with severe renal impairment (eGFR ≤ 30 mL/min/1.73 m2) or ESRD, due to higher exposure to the predominant sofosbuvir metabolite.

 

Side Effects: The most common side effects of the Panovir (sofosbuvir-velpatasvir) combination include headache and tiredness. Treatment may slow the heart rate and other symptoms when taken with amiodarone (a medicine used to treat certain heart problems).

 

Precautions: Serious symptomatic bradycardia may occur in patients taking amiodarone, particularly in patients also receiving beta-blockers or those with underlying cardiac comorbidities and/or advanced liver disease. Coadministration of amiodarone with the Sofosbuvir and Velpatasvir combination is not recommended. In patients without alternative viable treatment options, cardiac monitoring is recommended.

 

 

Use in Pregnancy & Lactation: No adequate human data are available to establish whether or not Sofosbuvir and Velpatasvir combination pose a risk to pregnancy outcomes. If Sofosbuvir and Velpatasvir combination is administered with Ribavirin, the combination regimen is contraindicated in pregnant women and in men whose female partner is pregnant or going to be pregnant in the next six months.

 

Drug Interaction: Drugs may decrease the concentrations of sofosbuvir and/or velpatasvir: Antacids, H2-receptor antagonists, Proton-pump inhibitors, etc.
Coadministration is not recommended with topotecan, Carbamazepine, Phenytoin, Phenobarbital, Oxcarbazepine, Rifabutin, Rifampin, Rifapentine, efavirenz, Tipranavir, Ritonavir, Hypericum perforatum.
Coadministration of Sofosbuvir and Velpatasvir combination, with Rosuvastatin, Atorvastatin may significantly increase the concentration of Rosuvastatin, Atorvastatin.

 

Overdose: If an overdose occurs the patient must be monitored for evidence of toxicity. Treatment of overdose includes monitoring of vital signs as well as observation of the clinical status of the patient.

 

Storage: Store in a cool and dry place (preferably below 30°C). Keep out of reach of children

How to order?

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  1. WhatsApp: You can send us a message on WhatsApp at +8801886229488 and one of our customer service representatives will assist you in placing your order.
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No matter which method you choose, our team is dedicated to providing you with personalized service and ensuring a smooth ordering process. If you have any questions or concerns, please don’t hesitate to contact us.

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  1. Western Union
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Once you have placed your order through one of our available methods (WhatsApp, WeChat, Messenger, or email), we will provide you with instructions for making payment via your preferred payment method. Once payment has been received, we will process and ship your order as soon as possible. Know about aio pharma at luckycapsules.com

If you have any questions or concerns about our payment options, please don’t hesitate to contact us. Our team is always available to assist you.

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