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Osimertinib/Tagrix/Osimert/Osicent Side Effect/Dosage & Administration

What is osimertinib?

Osimertinib is sometimes given when the cancer has spread to other parts of the body (metastatic), or may come back after surgery.

Osimertinib may also be used for purposes not listed in this medication guide.

Warnings

Osimertinib can cause serious side effects on your heart, lungs, skin, or eyes.

Before taking this medicine

You should not use osimertinib if you are allergic to it.

Tell your doctor if you have ever had:

  • lung or breathing problems;
  • an electrolyte imbalance (such as high or low blood levels of sodium, calcium, potassium, or magnesium);
  • eye problems; or
  • Osimertinib can harm an unborn baby if the mother or the father is using osimertinib.

    if the mother or the father is using osimertinib.
    If you are a woman,

  • If you are a man, use birth control if your sex partner is able to get pregnant. Keep using birth control for at least 4 months after your last dose.
  • If you are a man,

  • Tell your doctor right away if a pregnancy occurs.
  • Do not breastfeed while using this medicine, and for at least 2 weeks after your last dose.

    Do not breastfeed while using this medicine,

    Related/similar drugs

    How should I take osimertinib?

    Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

    Osimertinib is usually given once per day, with or without food.

    To make swallowing easier, you may place the tablet in a glass with about 2 ounces of water. Stir until the tablet is mostly dissolved and drink this mixture right away. Add 4 to 8 ounces more water to the glass, swirl gently and drink right away.

    You may need medical tests to check your heart function.

    Store at room temperature away from moisture and heat.

    What happens if I miss a dose?

    Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.

    What happens if I overdose?

    Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

    What should I avoid while taking osimertinib?

    Follow your doctor’s instructions about any restrictions on food, beverages, or activity.

    Osimertinib side effects

    signs of an allergic reaction
    or a severe skin reaction

    Osimertinib may cause serious side effects. Call your doctor at once if you have:

    Osimertinib may cause serious side effects. Call your doctor at once if you have:

  • skin redness or purple spots that don’t turn pale when pressed, and that still look red or bruised after 24 hours (may appear on your arms, legs, buttocks, or midsection);
  • redness, rash, or blisters on the palms of your hands or the soles of your feet;
  • new or worsening cough or trouble breathing;
  • fast or pounding heartbeats;
  • swelling in your lower legs, weight gain, feeling short of breath;
  • a light-headed feeling, like you might pass out;
  • Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.

    Common side effects of osimertinib may include:

    Common side effects of osimertinib may include:

  • low blood cell counts;
  • muscle, bone, or joint pain;
  • tiredness;
  • cough, mouth sores;
  • redness, tenderness, pain, or other problems with your fingernails or toenails.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Osimertinib dosing information

    Usual Adult Dose for Non-Small Cell Lung Cancer:

    Usual Adult Dose for Non-Small Cell Lung Cancer:

    useful content

    What other drugs will affect osimertinib?

    Osimertinib can cause a serious heart problem.